COVID-19 Associated Mucormycosis
نویسندگان
چکیده
Abstract This case series explores Covid-19 associated Mucormycosis (CAM), its risk factors, clinical features and outcomes from a tertiary centre in Maharashtra, India, during the second wave of COVID-19. Methods: A retrospective, observational 104 consecutive patients admitted to hospital at various stages complications CAM, COVID-19 pandemic (Jan’21-Apr’21). The diagnosis was confirmed using Potassium hydroxide wet mount (KOH), histopathology, fungal culture, Cone-Beam Computed Tomography(CBCT). Results: There were 81% men, mean age 49 ± 12.4 years, all had history corticosteroids usage, 82% prior diabetes mellitus (DM) rest newly diagnosed. Diagnosis mucormycosis on 2 modalities 71%; KOH histopathology 31 (30%), culture with together detected 25 (24%). 9% diagnosed exclusively CBCT. Patients DM higher morbidity OR 8.30 [95% CI: 2.12, 32.5; p=0.002] mortality 13.23 1.67, 104.7; p=0.014] than non-DM patients. Mortality rhino + orbital involvement maxillary [OR 8.37 1.52, 46.09; p=0.014]. Conclusion: Diabetes remained highest factor for development CAM corticosteroids, high morbidity. Timely medical surgical interventions multi-disciplinary approaches could potentially reduce mucormycosis-associated mortality. Among diagnostic modalities, detection CBCT may increase yield not other modalities.
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ژورنال
عنوان ژورنال: The physician
سال: 2023
ISSN: ['2732-513X', '2732-5148']
DOI: https://doi.org/10.38192/1.8.1.3